P/N: 036140001
The spherical plate 5D (SP5D) is a 3D cell culture plate for the formation of uniform, standardized spheroids with high quality and yield. It allows the effortless scaling and translation into the diagnostic or clinical application. At the same time, the reproducibility of follow-up tests increases, since the experiments always start under identical initial conditions due to the low size variance of the cultivated spheroids.
The patented geometry with special coating allows the integration of every single cell into a 3D-agglomerate in a controlled way. This is how uniformly sized spheroids grow without the formation of necrotic cores. According to the size and scale of the experiments, you can choose between our 24-well plate or our 6-well plate.
For small batches, we suggest using the 24-well plate containing 12 wells with 750 microwells each. Here, you will be able to yield up to 9,000 uniform spheroids. Furthermore, you can comfortably carry out monolayer comparative studies in the remaining 12 wells of the same plate.
The 6-well plate is suitable for scale-up trials and bigger batches. You can expect a yield of 3,364 spheroids per well, thus a total yield of 20,184 spheroids per plate.
The ready to use SP5D is particularly user-friendly: The cultivation does not require any pretreatment or centrifugation steps after seeding your cells. The media change is also particularly convenient due to simple pipetting, since the height of the microwells was chosen so that the cell clusters are retained. Moreover, the platform is compatible with standard automation units.
To find out how easy it is to work with the Sphericalplate 5D, watch our video here!
P/N: 036140002
The spherical plate 5D (SP5D) is a 3D cell culture plate for the formation of uniform, standardized spheroids with high quality and yield. It allows the effortless scaling and translation into the diagnostic or clinical application. At the same time, the reproducibility of follow-up tests increases, since the experiments always start under identical initial conditions due to the low size variance of the cultivated spheroids.
The patented geometry with special coating allows the integration of every single cell into a 3D-agglomerate in a controlled way. This is how uniformly sized spheroids grow without the formation of necrotic cores. According to the size and scale of the experiments, you can choose between our 24-well plate or our 6-well plate.
For small batches, we suggest using the 24-well plate containing 12 wells with 750 microwells each. Here, you will be able to yield up to 9,000 uniform spheroids. Furthermore, you can comfortably carry out monolayer comparative studies in the remaining 12 wells of the same plate.
The 6-well plate is suitable for scale-up trials and bigger batches. You can expect a yield of 3,364 spheroids per well, thus a total yield of 20,184 spheroids per plate.
The ready to use SP5D is particularly user-friendly: The cultivation does not require any pretreatment or centrifugation steps after seeding your cells. The media change is also particularly convenient due to simple pipetting, since the height of the microwells was chosen so that the cell clusters are retained. Moreover, the platform is compatible with standard automation units.
To find out how easy it is to work with the Sphericalplate 5D, watch our video here!
P/N: 036140001
The spherical plate 5D (SP5D) is a 3D cell culture plate for the formation of uniform, standardized spheroids with high quality and yield. It allows the effortless scaling and translation into the diagnostic or clinical application. At the same time, the reproducibility of follow-up tests increases, since the experiments always start under identical initial conditions due to the low size variance of the cultivated spheroids.
The patented geometry with special coating allows the integration of every single cell into a 3D-agglomerate in a controlled way. This is how uniformly sized spheroids grow without the formation of necrotic cores. According to the size and scale of the experiments, you can choose between our 24-well plate or our 6-well plate.
For small batches, we suggest using the 24-well plate containing 12 wells with 750 microwells each. Here, you will be able to yield up to 9,000 uniform spheroids. Furthermore, you can comfortably carry out monolayer comparative studies in the remaining 12 wells of the same plate.
The 6-well plate is suitable for scale-up trials and bigger batches. You can expect a yield of 3,364 spheroids per well, thus a total yield of 20,184 spheroids per plate.
The ready to use SP5D is particularly user-friendly: The cultivation does not require any pretreatment or centrifugation steps after seeding your cells. The media change is also particularly convenient due to simple pipetting, since the height of the microwells was chosen so that the cell clusters are retained. Moreover, the platform is compatible with standard automation units.
To find out how easy it is to work with the Sphericalplate 5D, watch our video here!
When developing the SP5D, the goal was to create the most realistic physiological environment possible for growing standardized spheroids with the possibility of cell-to-cell communication without external interfering signals. At the same time, the plate should allow real-time imaging and monitoring within the platform, be scalable and convenient to use.
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The SP5D provides a platform for generating 9,000 spheroids ...
Yes, it is possible ...
The fifth dimension ...
Since the cells do not attach to the surface, the spheroids are ...
Depending on the desired size of the spheroid to be formed ...
Depending on the cell line ...
Yes, there are several research groups ...
No additional equipment is needed besides the usual standard pipettes, buffer containers, a sterile work surface and an incubator ...